Francesca Ietta is a researcher at the Department of Life Sciences, University of Siena, Siena, Italy. She has spent several years as research fellow at the Department of Physiology, University of Siena. In November 2000, she started the PhD program in “Cellular Physiology and Neuroimmunophysiology” at the Department of Physiology, University of Siena. During her PhD studies, she worked for two years at the Samuel Lunenfeld Research Institute, Mont Sinai Hospital, Toronto, Canada (2002-2004). She is author or co-author of 33 full-papers in indexed Scientific International Journals, 4 papers in international books, and over 50 abstracts. She gave a great contribution to carried out research projects funded by the Italian Ministry for University and Research, the Tuscany’s Environmental Department and by the European Union. She has several national and international cooperations.
Molecular and Cellular Physiology: oxygen sensing in the normal and abnormal regulation of human trophoblast growth and differentiation.
Comparative Physiology: molecules involved in placentation of mammals and viviparous vertebrates.
Environmental Physiology: hormones-like environmental chemicals in the homeostasis of human placenta.
Dr. Roberta Romagnoli
Dr. Nicoletta Bechi
Dr. Chiara Mannelli
Dr. Claudiopietro Carotenuto
Endocrinology and Physiology of Reproduction
2nd year students of of Laurea Magistrale in Health Biology
Bechi N, Sorda G, Spagnoletti A, Bhattacharjee J, Vieira Ferro EA, de Freitas Barbosa B, Frosini M, Valoti M, Sgaragli G, Paulesu L, Ietta F. Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol. Toxicol. In Vitro 27, 995-1000 (2013).
Jantra S, Paulesu L, Lo Valvo M, Lillo F, Ietta F, Avanzati AM, Romagnoli R, Bechi N, Brizzi R. Cytokine components and mucosal immunity in the oviduct of Xenopus laevis (Amphibia, pipidae). General and Comparative Endocrinolog 33, 157-163 (2012).
Paulesu L, Bhattacharjee J, Bechi N, Romagnoli R, Jantra S, Ietta F. Pro-Inflammatory Cytokines in Animal and Human Gestation. Curr Pharm Des. 16, 3601-3615 (2010).
Rolfo A, Many A, Racano A, Tal R, Tagliaferro A, Ietta F, Wang J, Post M, Caniggia I. Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies. PLoS One 5, e13288 (2010).
Bhattacharjee J, Ietta F, Giacomello E, Bechi N, Romagnoli R, Fava A, Paulesu L. Expression and localization of ATP binding cassette transporter A1 (ABCA1) in first trimester and term human placenta. Placenta 31, 423-430 (2010).
Mørck TJ, Sorda G, Bechi N, Rasmussen BS, Nielsen JB, Ietta F, Rytting E, Mathiesen L, Paulesu L, Knudsen LE. Placental transport and in vitro effects of Bisphenol A. Reprod. Toxicol. 30, 131-137 (2010).
Bechi N, Ietta F, Romagnoli R, Jantra S, Cencini M, Galassi G, Serchi T, Corsi I, Focardi S, Paulesu L. Environmental levels of para-nonylphenol are able to affect cytokine secretion in human placenta. Environ. Health Perspec.t 118, 427-431 (2010).
Ietta F, Bechi N, Romagnoli R, Bhattacharjee J, Realacci M, Di Vito M, Ferretti C, Paulesu L. 17{beta}-Estradiol modulates the macrophage migration inhibitory factor secretory pathway by regulating ABCA1 expression in human first-trimester placenta. Am J Physiol. Endocrinol. Metab. 298, E411-8 (2010).
Ietta F, Wu Y, Romagnoli R, Soleymanlou N, Orsini B, Zamudio S, Paulesu L, Caniggia I. Oxygen regulation of macrophage migration inhibitory factor in human placenta. Am J Physiol Endocrinol Metab. 292, E272-80 (2007).
Ietta F, Wu Y, Winter J, Xu J, Wang J, Post M, Caniggia I. Dynamic HIF1A regulation during human placental development. Biol Reprod. 75, 112-21 (2006).