Claudia TORRICELLI

foto Claudia Torricelli
Biosketch and CV

Name: Claudia Torricelli

Place and date of birth: Siena 24/02/1965

University Education:  1989- Degree in Biological Sciences at the University of Siena, 110/110 “cum laude”.

Current position:  Assistant Professor of Physiology, Department of Life Sciences, University of Siena.

Previous position: 1991- 2002 Technical Assistant at the Institute of  General Physiology, University of Siena.

Teaching activity: General Physiology - Degree Course in Biological Sciences and  Natural Sciences. Pratical course of General Physiology  and Experimental Biology

Current Research activity:  Anti-cancer and anti-metastatic activities of natural compounds

Research Interests
  • Signal transduction and molecular mechanisms of cell proliferation  control.
  • Signal transduction and molecular mechanisms of cell death including apoptosis and caspase-independent novel types of cell death
  • Anti-cancer and anti-metastatic activities of natural compound
Research Group

Emanuela Maioli

Sara Salvadori

Elena Daveri

Teaching Activities
  • PAST:   1990-2002- Teaching assistant in General Physiology and General Physiology II-Degree in Biological Sciences and Natural Sciences. Pratical course of General Physiology  and Experimental Biology- Degree in Biological Sciences
    2002 – 2010- Teacher in  Animal and General Physiology- Degree in Biological Sciences
    2009-2010- Teacher in  Systems  Physiology Complements - Degree in Biological Sciences
  • PRESENT:   Teaching assistant in General Physiology -Degree in Biological Sciences.
Selected Publications
  1. C. Torricelli, S. Salvadori , G. Valacchi, K. Souček, E.  Slabáková,  M. Muscettola, N. Volpi, E. Maioli. Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy
     
  2. Evid. Based. Complement.  Alternat.  Med. 2012, 980658 (2012)
     
  3. E. Maioli, C. Torricelli,  G. Valacchi. Rottlerin and curcumin: a comparative analysis.  Ann.  N. Y. Acad.  Sci.  1259, 65-76 (2012)
     
  4. E. Maioli, C. Torricelli,  G. Valacchi. Rottlerin and cancer: novel evidence and mechanisms. Scientific World Journal.  2012, 350826 (2012)
     
  5. C. Torricelli, G. Valacchi, E. Maioli. Novel PKCs activate ERK through PKD1 in MCF-7 cells. In Vitro Cell.  Dev.  Biol.  Anim. 47, 73-81  (2011)
     
  6. G. Valacchi , A. Pecorelli, C. Sticozzi, C. Torricelli, M. Muscettola, C. Aldinucci, E. Maioli. Rottlerin exhibits antiangiogenic effects in vitro. Chem.  Biol.  Drug  Des. 77,  460-470 (2011)
     
  7. E. Maioli, C. Torricelli, V. Fortino, F. Carlucci, V. Tommassini, A. Pacini.  Critical appraisal of the MTT assay in the presence of Rottlerin and uncouplers.  Biol.  Proced. Online. 11  227-240 (2009)
     
  8. V. Fortino, C. Torricelli,  E. Capurro, G. Sacchi,  G. Valacchi, E. Maioli.  Antiproliferative and Survival Properties of PMA in MCF-7 Breast Cancer Cell. Cancer Invest.  26, 13 – 21  (2008)
     
  9. C. Torricelli,  V. Fortino,   E. Capurro,  G. Valacchi,  A. Pacini,  M. Muscettola,  K. Soucek, E. Maioli.  Rottlerin inhibits the NFk B/Cyclin-D1 cascade in MCF-7 breast cancer cells. Life Sci. 82, 638-643 (2008)
     
  10. V. Fortino, E. Maioli, C. Torricelli, P. Davis, G. Valacchi. Cutaneous MMPs are differntly modulated by environmental stressors in old and young mice. Toxicol.  Lett. 173, 73-79 (2007)
     
  11. C. Torricelli, V. Fortino, E. CAPURRO, G. Sacchi, P. Ponzo, A. Pacini, M. Muscettola, E. Maioli.  Role of PTHrp and PTHrp-engaged pathways in MCF-7 cells migration/invasion. Matrix Biol.    25, 104-111  (2006)