She was born in Siena on 10th April 1972. She graduated with honors in Biological Sciences at University of Siena in 1997 and obtained a Ph.D in Molecular Medicine. Currently she is Assistant Professor of Comparative Anatomy and Cytology and member of Teaching Committee for Degree in Molecular and Cellular Biology. She has published papers in international journals in the field of glycobiology of fertilization. Her research activity is mainly focused on glycobiology of cancer and normal cells, with particular regard to fucosylated biological molecules and to organelles organization, and on the liposomes as drug delivery systems.
Cancer cell biology.
Fucosylated molecules.
Liposomes as drug delivery systems.
Glycobiology of cellular interactions
Prof.ssa Floriana Rosati
Dott.ssa Cinzia Della Giovampaola
Dott.ssa Antonietta Capone
Cellular Biology (2002-2003) (Degree in Biological Sciences, University of Siena).
Animal Cell Biology (2006-2011) (Degree in Biological Sciences, University of Siena).
Cytology and Histology (2011) (Degree in Biological Sciences, University of Siena).
Animal Biotechnology (2006-2010) (Degree in Biotechnologies, University of Siena).
Cellular Biotechnology (2010-2013) (Degree in Molecular and Cellular Biology, University of Siena).
She has done also many hours of Histology Laboratory on the Teaching of Cytology and Histology of the Degree in Biological Sciences, carried out by Prof. Floriana Rosati.
D. Pasqui, L. Golini, C. Della Giovampaola, A. Atrei, R. Barbucci. Chemical and biological properties of polysaccharides-coated titania nanoparticles: the key role of proteins. Biomacromolecules 12, 1243-1249 (2011).
S. Aldi, C. Della Giovampaola, R. Focarelli, A. Armini, M. Ziche, F. Finetti, F. Rosati. A fucose-containing O-glycoepitope on bovine and human nucleolin. Glycobiology 19, 337-343 (2009).
F. Flori, L. Ermini, G.B. La Sala, A. Nicoli, A. Capone, R. Focarelli, F. Rosati, C. Della Giovampaola. The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen. Mol. Reprod. Dev.75, 326-335 (2008).
F. Flori, C. Della Giovampaola, R. Focarelli, F. Secciani, G.B. La Sala, A. Nicoli, G. Hale, F. Rosati. Epitope analysis of immunoglobulins against gp20, a GPI-anchored protein of the human sperm surface homologous to leukocyte antigen CD52. Tissue Antigens 66, 209-216 (2005).
S. Delle Monache, F. Flori, C. Della Giovampaola, A. Capone, G.B. La Sala, F. Rosati, R. Colonna, C. Tatone, R. Focarelli. Gp273 the ligand molecule for sperm-egg interaction in the bivalve mollusc Unio elongatulus binds to and induces acrosome reaction in human spermatozoa through a protein kinase C-dependent pathway. Biol. Reprod. 69, 1779-1784 (2003).
C. Della Giovampaola, F. Flori, L. Sabatini, L. Incerti, G.B. La Sala, F. Rosati, R. Focarelli. The surface of human sperm bears three differently charged CD52 forms two of which remain stably bound to sperm after capacitation. Mol. Reprod. Dev. 60, 89-96 (2001).
F. Rosati, A. Capone, C. Della Giovampaola, C. Brettoni, R. Focarelli. Sperm-egg interaction at fertilization: glycans as recognition signals. Int. J. Dev. Biol. 44, 609-618 (2000).
R. Focarelli, C. Della Giovampaola, R. Seraglia, C. Brettoni, L. Sabatini, M. Pescaglini, F. Rosati. Biochemical and MALDI analysis of the human sperm antigen gp20, homologue of leukocyte CD52. Biochem. Biophys. Res. Comm. 258, 639-643 (1999).
R. Focarelli, S. Francavilla, F. Francavilla, C. Della Giovampaola, A. Santucci, F. Rosati. A sialoglycoprotein, gp20, of the human capacitated sperm surface is a homologue of the leukocyte CD52: analysis of the effect of anti-CD52 monoclonal antibody (CAMPATH-1) on capacitated spermatozoa. Mol. Hum. Reprod. 5, 46-51 (1999).
R. Focarelli, A. Giuffrida, S. Capparelli, M. Scibona, F. Menchini Fabris, F. Francavilla, S. Francavilla, C. Della Giovampaola, F. Rosati. Specific localization in the equatorial region of gp20, a 20kDa sialylglycoprotein of the capacitated human spermatozoon acquired during epididymal transit which is necessary to penetrate zona-free hamster eggs. Mol. Hum. Reprod. 4, 101-107 (1998).