Cytoskeleton and Cell Motility in Animal Cells

The lab activities are focused on the morpho-functional analysis of cilia/flagella and their related structures in different eukaryotic models, using biochemical, immunomicroscopy and state-of-the-art ultrastructural strategies.  General interest in these organelles comes from their implication in the onset of an increasing series of human syndromes.

  • Centriole/centrosome biogenesis in Drosophila
  • Primary cilium dynamics during Drosophila spermatogenesis
  • Comparative ultrastructure and evolution of insect sperm flagella
  • Morphofunctional analysis and 3D modelling of Chlamydomonas flagella: i) fine ultrastructure of intraflagellar transport complexes, ii) transition zone ultrastructure and the control of ciliary trafficking.

Researchers involved in the activities:

Romano Dallai

Giuliano Callaini

Pietro Lupetti

Caterina Mencarelli

Maria Giovanna Riparbelli

Eugenio Paccagnini

Alessandro Gradi

Leonardo Masi

Laura Cresti

Silvia Ciolfi

Marco Gottardo (Post-doc, https://www.researchgate.net/profile/Marco_Gottardo)

Francesco Barbieri (PhD student)

Mariangela Gentile (PhD student, https://www.researchgate.net/profile/Mariangela_Gentile)

Veronica Persico (PhD student)

Ambra Pratelli (temporary staff member)